ALMA MATER STUDIORUM - UNIVERSITà DI BOLOGNA
Coordinator & PI: Paolo Blasi
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Isabella Orienti
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Marco Rinaldo Oggioni
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Carola Eleonora Parolin
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Aurora Botti
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Elisa Corazza
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Martina D’Alessandro
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Expertise, Role and Activity
The Department of Pharmacy and Biotechnology is composed by 170 fixed term professors, researchers and technicians, 118 PhD Students and about 60 Postdocs. The two main fields of investigation are the study of biological systems and molecular mechanisms underlying physiological and pathological processes and the development of innovative biotechnologies and the development of new drug and health products by taking advantage of the biochemical, physiological, pharmaco-toxicological, chemical and technological expertise.
PI: Paolo Blasi
the Project Coordinator, is Associate Professor of Pharmaceutical Technology with expertise in pharmaceutical nanotechnology, nanomedicine, drug delivery and targeting. The recent research in nanomedicine has been focused on the development of lipid nanoparticles for targeted brain drug delivery, lipid, polymer and metal nanoparticles for cancer targeting. In the BactEradiX project, Paolo is responsible for biofilm characterization (WP2), nanoparticle preparation, decoration and characterization (WP4) and nanoparticle platform optimization and characterization (WP6).
Isabella Orienti
is Full Professor of Pharmaceutical Technology with expertise in pharmaceutical nanotechnology for controlled drug delivery and targeting. Particular interests are focused to the design and preparation of innovative nanocarriers for ‘natural’ antitumor drugs with the aim to obtain a therapeutic response without toxicity in the long-term treatment of the minimal residual disease. In this project, Isabella is involved in nanoparticle preparation, decoration and characterization (WP4) and nanoparticle platform optimization and characterization (WP6).
Marco Rinaldo Oggioni
is Full Professor of Microbiology with expertise in the molecular mechanisms involved in the interaction of bacterial pathogens with their environment - the human host - by use of genomic tools, and in the molecular determinants of antimicrobial drug resistance and mechanisms governing mobile genetic elements. Marco is involved in nanoparticle anti-biofilm investigation (WP4), in the determination of bactericidal activity of anti-gene artificial oligonucleotide (WP5) and in the nanoplatform antimicrobial and anti-biofilm assessment (WP6).
Carola Parolin
is senior Assistant Professor, her research is focused on human microbial ecosystems (especially vaginal), the interaction among host-microbiota-pathogens, and the mechanisms underlying the health-promoting effect of probiotic bacteria, especially lactobacilli. In the project, Carola focuses on biofilm characterization (WP2), in Z-DNA targeting investigation and anti-biofilm activity (WP3) and in the nanoplatform antimicrobial and anti-biofilm assessment (WP6).
Aurora Botti
is a PhD student in the Cellular and Molecular Biology program at the University of Bologna (UNIBO). She holds a Master’s degree in Health Biology, with a thesis focused on the characterization of the vaginal microbiota. Following graduation, she spent two years as a research fellow working on projects related to bacteria–host interactions, specifically within the vaginal and intestinal microbiota. In the project, Aurora is involved in Z-DNA targeting and anti-biofilm activity (WP3) and assessing the antimicrobial and anti-biofilm properties of nanoplatform-based systems (WP6).
Elisa Corazza
is post-doctoral fellow with a scientific background in Pharmaceutical Biotechnology and Pharmaceutical Technology. Within her expertise are the development of nanovesicular systems and the characterization of the in vitro efficacy of some DNA analogs. In the BactEradiX project, Elisa is mainly responsible for nanoparticle preparation, decoration and characterization (WP4) and nanoparticle platform optimization and characterization (WP6)
Martina D'Alessandro
is a PhD student in Drug Discovery and Development. Her research experience includes preclinical studies in regenerative medicine and tissue engineering, with a particular focus on the histological and pathological aspects of musculoskeletal diseases. In the BactEradiX project, Martina is mainly involved in nanoparticle preparation, decoration and characterization (WP4) and nanoparticle platform optimization and characterization (WP6).
All the Consortium
